Streamline Global Patient Program Compliance with Zelthy

Introduction

Global pharmaceutical companies increasingly rely on Patient Support Programs (PSPs) to enhance access, adherence, and patient outcomes. However, as these programs expand across regions, they introduce significant challenges in regulatory compliance and oversight. Disparate systems, inconsistent policies, and siloed data environments make it difficult for global compliance teams to maintain visibility and respond proactively to risk.

This blog explores the challenges of monitoring global PSPs and how Zelthy’s Global Patient Program Monitoring Platform addresses these issues through centralized data management, AI-powered compliance workflows, and scalable governance infrastructure.

Challenges in Monitoring Global Patient Support Programs

1. Fragmented Data Systems

Each region often uses different data storage and reporting systems—ranging from local CRMs to third-party vendor tools—resulting in multiple datalakes with no unified oversight. This fragmentation prevents a single view of patient interactions and compliance status.

2. Inconsistent Policy Enforcement

While global SOPs may exist, their local implementation can vary significantly. Regional vendors and internal teams may interpret policies differently, increasing the likelihood of deviations and compliance gaps.

3. Vendor and Stakeholder Complexity

Large-scale PSPs often involve dozens of vendors, call centers, and service providers, each managing their own processes. Without a unified monitoring layer, it becomes difficult to assess whether each stakeholder is operating in line with global standards.

4. High Manual Workloads

Compliance teams spend considerable time chasing static reports, reviewing vendor submissions, and cross-checking compliance against policy documents—an inefficient and error-prone process.

Zelthy’s Solution: A Centralized Compliance Monitoring Solution for PSPs

Zelthy’s Global Patient Program Monitoring Platform is designed to solve these enterprise challenges with a technology-first approach. It consolidates program data, digitizes policy frameworks, and enables real-time oversight of global PSP operations.

Key Features and Benefits

• Centralized Compliance Datalake: The platform ingests structured and unstructured data from all PSP sources into a secure, unified environment. This eliminates silos and enables global teams to access a consolidated view of all ongoing programs and stakeholders.
• Policy Management Engine: Global and local compliance policies can be uploaded and configured within the platform. Each program’s operational data is continuously validated against these policies, flagging potential deviations automatically.
• Real-Time Monitoring of Vendors and Regions: Zelthy offers dashboards that allow real-time tracking of vendor activities, patient interactions, and support workflows—enabling early detection of non-compliant actions.
• AI-Driven Compliance Workflows: AI models analyze data against the uploaded policy rules and trigger alerts when anomalies or deviations are detected. This significantly reduces manual review and increases monitoring coverage.
• Automated, Audit-Ready Reports: Generate customizable compliance and operations reports by geography, vendor, or therapeutic area—streamlining internal reviews and regulatory inspections.

Why Global Pharma Companies Choose Zelthy

Pharmaceutical leaders choose Zelthy to streamline oversight across complex, multi-country patient support ecosystems. The platform offers:

• A unified system to manage PSPs run by diverse vendors across geographies.
• Built-in policy enforcement aligned with HIPAA, GDPR, and market-specific regulations.
• Real-time alerts and AI-driven flagging of policy deviations to reduce compliance risk.
• Automation that significantly cuts manual workload for compliance and operations teams.
• Proven success in accelerating program approvals, improving adherence, and reducing costs—as seen in deployments across Australia and APAC.

For instance, a top pharma in Australia reduced PSP approval times by 65% after migrating from paper-based workflows to Zelthy’s digital platform. Another oncology PSP achieved a 45% boost in adherence and a 60% faster enrollment process through the platform’s patient-centric modules.

These results highlight why pharma companies globally are turning to Zelthy to modernize compliance, improve program efficiency, and scale PSPs with confidence.

You can read the full case study here and find out how a leading pharma boosts cancer therapy adherence in Australia.

Conclusion

As patient support programs continue to expand across borders, pharma companies need more than regional dashboards and vendor PDFs to manage compliance. They need a centralized, scalable platform that aligns with enterprise data governance standards and regulatory expectations.

Zelthy’s Global Patient Program Monitoring Platform delivers this capability, helping compliance and ethics leaders stay ahead of risk, improve transparency, and drive operational efficiency across PSP ecosystems.

Schedule a demo to see how Zelthy can transform your global PSP monitoring into a streamlined, compliant, and data-driven operation.